Symptoms of chronic Epstein Barr virus infection

summary

A few days ago, the child of one of my colleagues was just born and infected with cytomegalovirus. The child has symptoms of fever, sore throat, headache, body pain, etc. the doctor said: its clinical manifestations are quite similar to infectious mononucleosis caused by EB virus infection, but the heterophilic agglutination test is negative. It sounds really surprising, How can such a small child be infected with such a serious virus? The symptoms of slow living Epstein Barr virus infection, let me tell you.

Symptoms of chronic Epstein Barr virus infection

It is one of the important ways of human cytomegalovirus infection. 90% of the infected fetuses are recessive infection, only 10% of them are clinical infection, but sometimes the consequence is more serious.

Acquired infection of cytomegalovirus in infants, mostly recessive infection or mild symptoms, but the clinical manifestations of a few patients are more serious, perinatal infection of neonatal patients, some of them may be intrauterine infection, can be persistent pneumonia, children and adult patients can develop cytomegalovirus hepatitis.

Ganciclovir and foscarnet sodium are two kinds of antiviral drugs for the treatment of CMV infection. They have been used in the treatment of AIDS patients, patients with CMV infection after organ transplantation, or prophylactic drugs after organ transplantation, but the clinical effect is not very ideal.

matters needing attention

Cytomegalovirus mainly invades epithelial cells. The main organs (lung, liver, brain, kidney, spleen, heart, intestine), glands (salivary gland, gonad) and nervous system can be involved. The infected cells degenerated, increased in size, presented as giant cells, and then disintegrated, leading to local necrosis and inflammation.