Can gastrocnemius atrophy be inherited?

summary

Many people don't know what kind of disease is caused by Charcot Marie Tooth disease, but the society is developing too fast, the pollution is too serious or what's wrong. We haven't touched the case terms detected before. Can Charcot Marie Tooth disease be inherited? Next, I'll give you a brief introduction.

Can gastrocnemius atrophy be inherited?

The first is that Charcot Marie Tooth disease can be inherited. About 80% of the patients are hereditary in the family, and about 20% are sporadic; Most of them are close relatives. Most of them are autosomal dominant.

Second, the pathological changes were mainly in muscles and peripheral nerves. Most of the muscles are neurogenic atrophy, but myogenic atrophy, or a mixture of the two, can also be seen. There were segmental demyelination, regeneration, axonal degeneration, reduction of myelinated fibers and hyperplasia of connective tissue in peripheral nerves.

Third, the disease is caused by hereditary defects of Schwann cells or axons in peripheral nerves, which may be related to immunity in recent years. Patients may have thymus and intestinal immune mechanism is not perfect, let some exogenous substances such as lentivirus through the intestinal mucosa, the genetic susceptibility of individual invasion and disease.

matters needing attention

Peroneal atrophy is a hereditary progressive peripheral neuropathy. The most common symptoms were early slow running, weakness and atrophy of fibular muscle, extensor digitorum longus and small muscle of foot.