What causes Down syndrome

summary

Down syndrome is a common disease in pediatrics, which is mainly caused by chromosomal aberrations. Sixty percent of the fetuses suffering from Down's syndrome in the fetal period will miscarry in the early stage of the fetus. Even the later surviving fetuses will have obvious mental retardation, special face, growth and development disorders and multiple deformities after birth. The etiology of the disease has different concentrations, and genetic factors are one of the important reasons. If the mother is down's syndrome Patients, then the suggestion is not to give birth, the child will be genetic, also suffering from Down syndrome, let's take a specific look

What causes Down syndrome

First of all, genetic factors are very important causes of Down's syndrome, because Down's syndrome is due to the mutation of the patient's gene, one more chromosome 21, and the general male patients have no fertility, while the female patients will inherit the disease after childbearing.

Second: secondly, the incidence rate of Down syndrome is directly related to the age of the mother. The higher the age of pregnant women, the greater the probability of producing children with Down syndrome. As the age increases, the mother's egg quality will decrease, and the chance of causing twenty-one dyed abnormalities will increase.

Third: finally, the pathogenic factors in late pregnancy will also cause the fetus to suffer from Down's syndrome. For example, pregnancy sepsis will easily lead to insufficient blood supply to the fetus and affect the oxygen supply to the fetal brain tissue, which will easily lead to fetal growth retardation and toxic damage

matters needing attention

The heredity of Down's syndrome is very strong, so in line with the principle of eugenics, it is suggested that patients with Down's syndrome terminate pregnancy. For those parents who have given birth to a sick child, the risk of having another child will be very high, so more attention should be paid.