What are the symptoms of trisomy 21?

summary

Trisomy 21 syndrome, also known as Down's syndrome or Down's syndrome, is an autosomal aberration genetic disease. Its etiology is related to maternal age of pregnancy, genetic factors, abortion with chemical drugs during pregnancy, radiation exposure, autoimmune diseases and virus infection. 21 the incidence rate of somatic syndrome increases with the age of the mother. What are the symptoms of trisomy 21? Let's talk about it

What are the symptoms of trisomy 21?

Clinical features: 1. Children with special facial features, short head, round and flat face. The angle of the eye is inclined upward, the distance between the two eyes is far, the inner angle of the eye fissure, epicanthus, nystagmus. The bridge of the nose is low and flat, and the nostrils are upturned. The mouth is small, the mouth is half open, the palatal arch is high, the lip is thick, the tongue is thick, often stretches out the mouth, often giggles, looks very dull. The ears are small and round with low position.

2. Chest, abdomen, neck and back are short and wide, which may be accompanied by congenital heart disease. Abdominal distention, often accompanied by rectus abdominis separation, umbilical hernia, digestive tract deformity.

3. The muscle tension of the limbs is low, the joints of the limbs are soft, the hands are wide and thick, the fingers are short and small, the end of the little finger often bends inward, and the thumb of the foot is far away from the other four fingers.

matters needing attention

At present, there is no effective treatment, so we should pay attention to the training and education of children γ— Aminobutyric acid, osteolysine, folic acid, vitamin B6 to promote intellectual development and physical improvement.