What are the causes of lung cancer

summary

Advanced lung cancer is really painful. My uncle has been suffering from lung cancer for three years. After countless treatments, he is now diagnosed with advanced lung cancer. He looks very pitiful, but he is still undergoing chemotherapy. What are the causes of lung cancer!

What are the causes of lung cancer

First, lung cancer occurs in bronchial mucosa epithelium, also known as bronchial lung cancer. Lung cancer generally refers to the cancer of lung parenchyma. The exact cause of lung cancer is still unknown. After many years of investigation and research, it is recognized that the following factors are closely related to the etiology of lung cancer. Smoking: long term smoking can cause hyperplasia of bronchial epithelial cells, phosphorous epithelia, squamous cell carcinoma or undifferentiated small cell carcinoma. It is recommended to reduce smoking or quit smoking, which is good for yourself and the people around you.

Second: it has been recognized that long-term exposure to radioactive substances such as uranium, radium and their derivatives, carcinogenic hydrocarbons, arsenic, chromium, nickel, copper, tin, iron, coal tar, asphalt, petroleum, asbestos, mustard gas and other substances can induce lung cancer, mainly squamous cell carcinoma and undifferentiated small cell carcinoma; chronic lung diseases such as tuberculosis, silicosis, pneumoconiosis can coexist with lung cancer. The internal factors of human body, such as family heredity, decreased immune function, metabolic activity and endocrine dysfunction, may also play a certain role in the pathogenesis of lung cancer.   

Third: at present, smoking is considered to be the most important risk factor for lung cancer. There are more than 3000 chemical substances in tobacco, among which multi chain aromatic hydrocarbons (such as benzopyrene) and nitrosamines have strong carcinogenic activity. Multi stranded aromatic hydrocarbons and nitrosamines can lead to DNA damage in bronchial epithelial cells through a variety of mechanisms, which can activate oncogenes (such as Ras gene) and inactivate tumor suppressor genes (such as p53, FHIT gene), and then lead to cell transformation and finally canceration.

matters needing attention

All in all, from the above, smoking is one of the main factors of lung cancer. In fact, once patients find their own condition, they must go to the regular hospital for treatment as soon as possible to avoid delaying the disease. At the same time, they should not touch alcohol and tobacco, so that they can control the disease as soon as possible.