How much do you know about the pathology of psoriasis

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Psoriasis is a common chronic skin disease, can occur in any part, how much do you know the pathology of psoriasis? Mastering the pathological characteristics of psoriasis is very helpful for the treatment of psoriasis. So let me share some of my knowledge about psoriasis with you!

How much do you know about the pathology of psoriasis

First of all, we need to understand the pathogenesis of psoriasis: the glial layer cells in the epidermis of patients with psoriasis can not fully mature and become cells with incomplete keratosis. There is a gap filled with air between the cell bundles. Clinically, the scales are silvery white mica like, which is due to the incomplete keratosis with air and the refraction of light from the stratum corneum. It is in or under the stratum corneum of parakeratosis. Neutrophils whose cells have been destroyed are often seen. These groups of white blood cells mixed with some degenerative epidermal cells to form micro abscess, which is called Monroe micro abscess. It is one of the pathological features of psoriasis. But Monroe micro abscess can also appear in seborrheic dermatitis, continuous acrodermatitis and purulent catarrhal keratosis.

Secondly, in the dermis of the patient, there are cell infiltration around the superficial blood vessels, mainly lymphocytes. Especially special, the top of the nipple edema and swelling into a pestle shape, deeply embedded in the epidermis and close to the cuticle of the skin surface, therefore, in clinical practice, when the scales are stripped, it is easy to expose the nipple, and easy to damage the blood vessels of the nipple and cause bleeding spots. The collagen, elastic and reticular fibers of the dermis were denatured to a certain extent.

Finally, the types of psoriasis are also different: pustular psoriasis, continuous acrodermatitis and herpetic pustulosis have the same histological changes, and they all have spongy COGO medium micro abscess. Due to the rupture of edematous epidermal cells, the cell wall is connected into a sponge, and the neutrophils in the dermis migrate to the cavernous blister cavity and become a sponge like abscess, that is, COGO's medium micro abscess, which is easy to appear in the upper part of the epidermis. When the abscess advanced to the stratum corneum with epidermal cells, it became a larger Monroe abscess.

matters needing attention

Many friends suffering from psoriasis know that although psoriasis can not directly affect life, but for the sick people, it has serious harm to physical and mental health. Psoriasis can be induced by mental pressure, emotional depression, overwork, environmental changes, and many other reasons. So psoriasis will be cured for a long time, repeated attacks! In order to completely remove psoriasis, we must first maintain a positive attitude and spirit, and at the same time take reasonable and correct treatment measures to really get rid of the trouble of psoriasis.