Nipple has small flesh grain, take cauliflower shape?

summary

Condyloma acuminatum is a very common disease at present. In the process of condyloma acuminatum, it will lead to cauliflower like small meat particles in the breast, oral cavity, genital system and other sensitive parts of the patient. At the beginning, small meat particles are easy to fall off, accompanied by secretions. With the extension of time, it will spread, and even become hard small barbs, So the nipple has a small meat like cauliflower like symptoms, need to be checked in time to the hospital.

Nipple has small flesh grain, take cauliflower shape?

The epidermis was papillomatous hyperplasia and the spinous layer was hypertrophic. There were mild hyperkeratosis and parakeratosis on the surface. Vacuolized cells can be seen in the spinous cells and granular layer. The cell body is large, with a round and deeply stained nucleus, vacuolized and lightly stained around the nucleus. There are filaments connected between the nuclear membrane and serosa, making the cells look like cat's eyes. Vacuolized cells are characteristic findings of condyloma acuminatum, especially in the middle and upper layer of spinous cells. In the superficial dermis, there was medium density infiltration around blood vessels, mainly lymphocytes and plasma cells. The dermal papilla was dilated and widened.

Wrap or apply the gauze soaked in 3% ～ 5% acetic acid solution on the surface of suspicious skin or mucous membrane, and remove it after 3 ～ 5 minutes. Typical condyloma acuminatum lesions will show white papules or wart vegetations, while subclinical infections will show white patches or spots. Vinegar white test is a simple method to identify early condyloma acuminatum damage and subclinical infection. It is a very useful method to detect subclinical infection without visible changes. Vinegar white test is simple and easy to operate. It should be used as a routine examination method for patients with condyloma acuminatum, which is helpful to determine the scope of lesions and guide treatment. However, the vinegar white test is not a specific test. It can show false positive results for epithelial cell proliferation or initial healing after trauma.

Colposcope is a special magnifying glass, which is mainly used for the observation of cervical and vaginal mucosa, and can be used for the examination of vulva and vaginal epithelium. Colposcopy can magnify the cervical manifestations 20-40 times, which is very helpful for subclinical infection of cervical epithelium, early detection and early diagnosis of precancerous lesions. Patients should avoid vaginal flushing and sexual intercourse 24 hours before examination. It is helpful to find subclinical infection of HPV by colposcopy after 3 minutes application of gauze soaked in 3% - 5% acetic acid solution. For clear white patches or spots, further histopathological examination should be performed. Cervical intraepithelial neoplasia (CIN) can be divided into three grades.

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DNA was extracted from diseased tissues or suspicious parts, and the target DNA was amplified by specific primers. The primers can be either universal or specific for HPV. The method has high sensitivity and specificity, but it should be carried out in the laboratory recognized or certified by relevant institutions.