How to calculate the ratio of creatinine and urea nitrogen?

summary

The ratio of urea nitrogen to creatinine is the ratio of urea nitrogen to creatinine; In addition, the study of urea nitrogen creatinine ratio has clinical significance. How to calculate the ratio of creatinine and urea nitrogen? Let's share my experience with you.

How to calculate the ratio of creatinine and urea nitrogen?

SCR (creatinine) and bun (urea nitrogen) can reflect the damage degree of glomerular filtration function to a certain extent. Bun is also affected by extrarenal factors, such as high protein diet, gastrointestinal bleeding, dehydration and high catabolism, which can increase bun.

Under the condition of stable exogenous creatinine intake and constant creatinine production, SCR (creatinine) mainly depends on glomerular filtration capacity, so it is more accurate than bun (urea nitrogen). Therefore, the observation of the ratio of serum urea nitrogen to creatinine has certain clinical significance.

Hyperabsorption of urea: prerenal, dehydration, cardiac insufficiency, hypoproteinemia, hypovolemia, hepatorenal syndrome. Retrorenal: urinary tract obstruction, ureterostomy. Congenital renal tubular hyperuricemia (familial hyperuricemia).

matters needing attention

1. It will cause the disorder and disorder of metabolism in the body, such as sodium metabolism, potassium metabolism, water electrolyte disorder, resulting in hyperemia and hypoemia, as well as the symptoms of polyuria, nocturia and edema. 2. It will cause abnormal trace elements in the body.