What reason is hyaluronic acid high

summary

Hyaluronic acid high in today's society is more common, because now the diet and living habits will be very easy to cause, hyaluronic acid, also known as hyaluronic acid, is an acid mucopolysaccharide. It is an important basic material for tender skin, and it is also a component of human body. It has a special water retaining effect, and its weight is up to 100 times of its own weight. It is the best moisturizing substance in nature, known as the ideal natural moisturizing factor. It can improve the nutrition metabolism of skin, make skin soft, smooth, wrinkle free, increase elasticity, prevent aging, and is a good transdermal absorption promoter while moisturizing. Combined with other nutrients, it can promote the absorption of nutrients.

What reason is hyaluronic acid high

First: animal tissue: the main raw materials are chicken crowns and bovine eyes. The raw materials were degreased and dehydrated with acetone or ethanol, soaked and filtered with distilled water, then treated with sodium chloride solution and chloroform solution, then added with trypsin to keep warm to obtain the mixed solution, and finally treated and purified with ion exchanger to obtain refined hyaluronic acid. The extraction rate of this method is very low, only about 1%, and the separation process is complex. As a result, the price of hyaluronic acid is expensive, up to 5000 US dollars / kg, which limits the large amount of use in cosmetics.

Second: microbial fermentation: glucose as carbon source fermentation broth. After fermentation in medium for 48 hours, the mycelium and impurities were removed by filtration, and then the high purity product was obtained by simple operation such as alcohol precipitation method. Hyaluronic acid produced by fermentation has the advantage of being able to set the molecular weight according to the commercial design. The key of fermentation method is the selection of strains, such as Streptococcus and Lactococcus.

Third: chemical synthesis: the natural enzyme polymerization reaction is adopted; firstly, the polysaccharide polymer is used to synthesize the "hyaluronic acid oxocyclopentene derivative", then the water decomposing enzyme is added to make the complex of derivative and enzyme, and finally the enzyme is removed in the 90 ℃ reaction solution to synthesize hyaluronic acid. The synthetic method can greatly reduce the production cost of hyaluronic acid, but the structure is not pure.

matters needing attention

The same product is hyaluronic acid, because of the difference of raw material source and manufacturing technology, which has a significant impact on the effect. The concentration of the product can not be used as a reference for the selection of products. The purity, molecular weight and 3D structure will directly affect the water absorption effect of hyaluronic acid. Generally, the larger the molecular weight and the more complete the network structure, the better the water absorption effect. Maintenance products and cosmetics are popular in the market, but hyaluronic acid made by many manufacturers is cheap, but not necessarily effective. Some people even advocate that oral hyaluronic acid can be broken down into small unit molecules of carbohydrate and amino acid after being absorbed by the intestines and stomach. It can only be produced in the skin and connective tissue through autosynthesis and other steps, and its effect must be discounted.