Myeloma pain symptoms?

summary

Multiple myelomatosis is a kind of malignant plasma cell disease. The tumor cells originate from the plasma cells in bone marrow, and the plasma cells are the cells that develop to the final functional stage of B lymphocytes. Due to the lack of understanding of multiple myeloma, many people do not know that they have multiple myeloma. Sometimes they may find that they have multiple myeloma only after routine physical examination

Myeloma pain symptoms?

The symptoms of multiple myeloma include bone and joint pain, low back pain, osteoma of skull and chest rib, bead like nodule at the junction of chest rib and clavicle, osteolytic drill like or rat bite like round bone defect, pathological fracture, paraplegia, intercostal and sciatic neuralgia, etc.

Dizziness, headache, visual impairment, chest tightness, vertigo, bleeding and other symptoms caused by increased blood viscosity. It is easy to cause lung and urinary tract infection. The most common age is over 40 years old, male is more than female.

Anemia and bleeding: anemia is another common clinical manifestation of multiple myeloma. Clinically, it is found that the vast majority of patients with multiple myeloma have different degrees of anemia in the course of the disease, and some of them seek medical treatment with anemia symptoms as the main complaint; Among them, the degree of anemia is different, the general course of disease is lighter in the early stage and heavier in the late stage.

matters needing attention

Kidney damage: multiple myeloma can cause certain damage to people's kidneys, mainly due to abnormal monoclonal immunoglobulin overproduction and imbalance of heavy chain and light chain synthesis. Excessive light chain is generated, and only 23000 light chain with relative molecular weight can be filtered from renal glomeruli and reabsorbed by renal tubules. Excessive light chain reabsorption causes renal tubular damage, Renal lesions can be seen.