Is skin toxoplasmosis dangerous?

summary

Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. Where there are living things, there are almost all arched bodies. Toxoplasma gondii is a kind of coccidia parasitized in cells. There are congenital infection and acquired infection. The human body has innate immunity to Toxoplasma gondii and its clinical manifestation is acute infection. Severe cases can be fatal. Only a small part of the infected patients had clinical symptoms, and most of them were subclinical. The skin rash of congenital toxoplasmosis was mainly ecchymosis and purpura; Acquired toxoplasmosis, except for a few serious cases, is generally mild with complex and diverse symptoms. Is skin toxoplasmosis dangerous?

Is skin toxoplasmosis dangerous?

Clinically, there are different clinical manifestations depending on the organs and tissues involved. The skin manifestation of this disease is nonspecific. Treatment commonly used sulfonamides, Acetylspiramycin, clindamycin, can also be injected to patients with Toxoplasma gondii. Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii.

The human body has innate immunity to Toxoplasma gondii. After infection, it forms cysts in the tissues, showing recessive infection but no disease. Once the body's immune function decreases, it shows symptoms of acute infection. Only a small part of the infected patients had clinical symptoms, and most of them were subclinical. Severe cases can be fatal. In the acute stage of the disease, protozoa can invade various tissues, form granuloma and cause tissue necrosis.

Only a small part of the infected patients had clinical symptoms, and most of them were subclinical. The skin rash of congenital toxoplasmosis was mainly ecchymosis and purpura; Acquired toxoplasmosis, except for a few serious cases, is generally mild with complex and diverse symptoms. The skin showed macular papules and subcutaneous nodules on the scalp, palm and other parts of the foot; It can also be seen as ring-shaped wheal, papule or even blister; The limbs and trunk may present typhus like and scarlet fever like rashes. Most of the lesions appeared one week after the onset of the disease, and disappeared two weeks later. In the acute stage of the disease, protozoa can invade various tissues, form granuloma and cause tissue necrosis. Clinically, there are different clinical manifestations depending on the organs and tissues involved.

matters needing attention

Treatment of sulfonamides: the combination of pyrimidine and sulfamethoxamidine, each course of 1 month, interval 30 days before the next course of treatment, can be repeated several courses. The dosage of Sulfamethoxine was 2-4 g / D, and that of uracil was 25-50 mg / d. after 2 days, it was changed to 25 mg / d. Blood picture should be observed during treatment. Pyrimethamine has teratogenic effect and should be used with caution in pregnant women; The drug is a folic acid antagonist, so it should be given folic acid. Only a small part of the infected patients had clinical symptoms, and most of them were subclinical. Severe cases can be fatal. The animal hosts of the disease are very wide, so it is necessary to manage livestock to prevent water pollution. Do not drink raw water, do not eat undercooked meat, dairy products. Children should not play with animals such as cats and dogs.