How is coagulase negative Staphylococcus treated
summary
According to the proportion of Staphylococcus isolated from different infected parts in different areas, the possible way of understanding is different, the possibility of Staphylococcus infection should be judged according to the clinical manifestations, and antibiotics should be selected according to the drug sensitivity spectrum of Staphylococcus isolated recently. At present, all over the world reported penicillin sensitive Staphylococcus, coagulase negative Staphylococcus how to treat tell you.
How is coagulase negative Staphylococcus treated
Method 1: general treatment, timely diagnosis and early application of appropriate antibiotics are the key to success in the treatment of severe staphylococcal infection. In addition to antibiotics, we should also pay attention to improving the human immune function, correcting the disorder of water and electrolyte, rescuing septic shock and protecting the function of heart, lung, kidney, liver and other important organs. Whether to use adrenocortical hormone or not must be decided after full consideration of its advantages and disadvantages. Unless there is severe toxemia and it is combined with effective antibiotics, it is generally appropriate not to use adrenocortical hormone. Human serum gamma globulin (gamma globulin) is suitable for patients with antibody deficiency diseases such as hypoglobulinemia.
Method 2: adequate drainage of pus is often a prerequisite for the treatment of staphylococcal infection with abscess. Superficial infections such as furuncle, paronychia, and palpebral adenitis can be cured quickly after self perforation or incision and drainage of pus. Generally, antibiotics are not needed. Deep subcutaneous abscess or osteomyelitis with abscess formation should be incision and drainage, lung abscess can take position drainage, these infections should be treated with antibiotics. Multilocular liver abscess mainly depends on drug treatment, and surgical drainage should be considered when the effect of medical drug treatment is not satisfactory. When the artificial heart valve or venous intubation is accompanied by Staphylococcus infection, the valve must be replaced or the intubation must be removed. Antibiotics alone can not control the infection. The medical treatment of acute Staphylococcus aureus endocarditis is not effective. Repeated embolism or acute heart failure are the indications of operation.
Method 3: active antimicrobial therapy should be used immediately when patients with staphylococcal infection have systemic symptoms or local lesions show a trend of rapid development.
matters needing attention
There are several kinds of antibiotics used in staphylococcal infection: ① β - lactams: including penicillins, cephalosporins, imipenem; ② glycopeptides such as vancomycin, bacitracin, teicoplanin; ③ erythromycin and other macrocyclic antibiotics; ④ lincomycin and clindamycin; ⑤ aminoglycoside antibiotics such as gentamicin, amikacin, netilmicin; ⑤ aminoglycoside antibiotics such as gentamicin, amikacin, netilmicin; ⑤ antibiotics such as antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics, antibiotics; ⑥ Rifamycin such as rifampicin; 7 quinolones such as ciprofloxacin; 8 semi synthetic tetracyclines such as doxycycline and minocycline; 9 sulfamethoxazole / trimethoprim (compound sulfamethoxazole); 10 others such as chloramphenicol and fosfomycin. In China, oxacillin, cloxacillin, vancomycin, erythromycin, gentamicin, rifampicin, fosfomycin and so on are widely used.
