What are the susceptibility genes of pancreatic cancer

summary

Uncle used to be a patient with pancreatic cancer. He saw the disease torture him with his own eyes. He also died of pancreatic cancer. I don't know what the susceptibility genes of pancreatic cancer are. Next, let me talk about the susceptibility genes of pancreatic cancer.

What are the susceptibility genes of pancreatic cancer

First: Lin Dongxin and Wang Chengfeng of Institute of oncology, cancer hospital, Chinese Academy of Medical Sciences cooperated with a number of domestic scientific research institutions in a study of pancreatic cancer susceptibility genes with the largest sample size in the world, and found five new pancreatic cancer susceptibility genes. This research result was published online in the world's top professional journal Nature Genetics recently.

Second, pancreatic cancer is a kind of tumor with high malignancy and poor prognosis. The 5-year survival rate of patients is generally less than 5%, which is worthy of the name of "king of cancer". One of the main reasons for poor prognosis of pancreatic cancer is that there is no effective early detection method. Although surgical resection is the best treatment for pancreatic cancer, most patients have lost the opportunity of surgical treatment. Therefore, it is very important to find biomarkers for early detection and diagnosis of pancreatic cancer.

Third: in September 2010, Lin Dongxin, laboratory of etiology and carcinogenesis, Institute of oncology, cancer hospital, Chinese Academy of Medical Sciences, cooperated with Wang Chengfeng, Department of abdominal tumor surgery, and cooperated with 21 scientific research institutions, including Huazhong University of science and technology, Fudan University, China Medical University, and the Second Military Medical University, to collect 3584 patients with pancreatic cancer from 25 hospitals in 16 provinces and cities, and 4868 healthy people The control group was included in the study.

matters needing attention

Pancreatic cancer is a very harmful disease, which is no doubt and can reach a consensus. There are many causes of pancreatic cancer, among which genetic variation of five chromosome regions in human body is the predisposing factor of pancreatic cancer.