What symptom does congenital anemia have?

summary

Anemia is often encountered in our life, but there are many kinds of anemia, and there are many causes of anemia. There are inherited anemia and acquired deficiency anemia. Congenital aplastic anemia is an autosomal recessive genetic disease. In addition to the reduction of the number of whole blood cells, it is also accompanied by multiple congenital malformations and other symptoms.

What symptom does congenital anemia have?

This disease is characterized by multiple malformations, such as microcephaly and strabismus; Most of the children have skeletal deformities, most of which are torsion and thumb deficiency. Some of them are mentally retarded, and most of the boys have genital hypoplasia. Anemia is the main manifestation, accompanied by thrombocytopenia. Due to the slow development of the disease, there was no bone marrow abnormality at the onset of the disease, and erythroid hyperplasia and megajuvenility could be seen.

Patients with severe congenital anemia are asymptomatic at birth, and will begin to develop at three months. They will have chronic progressive anemia, pale complexion, dysplasia, mild jaundice, and the symptoms will become more and more significant with time. Due to the compensatory hyperplasia of bone marrow, the bone became larger, which first occurred in the palm, then in the long bone and ribs; After one year of age, there will be obvious changes in the skull of infants, such as the enlargement of the skull, the protrusion of the forehead, the collapse of the bridge of the nose, the widening of the distance between the eyes, and the gradual formation of a special face with anemia.

When complicated with hemosiderosis, the most likely cause is heart failure, which is one of the important causes of death in children. Mild patients were asymptomatic. Intermediate type of patients with childhood moderate anemia, there will be gangrene, bone changes lighter symptoms.

matters needing attention

The general symptoms of congenital anemia are as follows: the patient has mental retardation since childhood, slow growth and development, and with the growth of age, the development gradually stops, and there are more congenital malformations. Hope that through the understanding of the symptoms of congenital anemia, in life can be found in time, give the correct treatment.