How to give first aid when myasthenia gravis is critical

summary

My aunt has been ill for six years, with muscle atrophy and myasthenia gravis. Better after treatment, let's take a look at how to give first aid when myasthenia gravis is critical.

How to give first aid when myasthenia gravis is critical

Treatment 1: adrenocortical hormone. Myasthenia gravis is an autoimmune disease. Suprarenal cortical hormone is a commonly used drug in the treatment of autoimmune diseases. At present, high-dose shock therapy, medium dose shock therapy and low-dose maintenance therapy are generally used in the treatment of myasthenia gravis in China. Studies have confirmed that adrenocortical hormone is an inducer of thymocyte apoptosis It can induce thymocyte apoptosis in vivo and in vitro.

Treatment 2: azathioprine, which is a non-specific immunosuppressant, can inhibit the synthesis of DNA, RNA and protein, thereby inhibiting gene replication and T cell activation, playing a role in the treatment of myasthenia gravis. Indications: the dosage of adrenocortical hormone should be reduced; adverse reactions: neutropenia, abnormal liver function, etc. Studies have shown that long-term use of azathioprine can increase the risk of malignant tumor.

Treatment 3: cyclophosphamide. Cyclophosphamide is a compound composed of nitrogen mustard and phosphoramide group. It is a commonly used alkylating agent immunosuppressant in clinic. It can be used for the treatment of various autoimmune diseases. Generally, the symptoms begin to improve within 2 months, and the dosage is reduced and maintained after 5 years. Indications: it is only used for those who are ineffective or intolerable to other mg drugs; adverse reactions: leukopenia, alopecia, hemorrhagic cystitis, etc.

matters needing attention

For such a disease: exercise is also one of the diagnosis and treatment of myasthenia gravis, but we should pay attention to a degree, to the right amount. Experts said that exercise is the most reliable method, can ask a special person to help patients with appropriate exercise, so as not to detect contracture. However, strenuous exercise, exertion and over active physical therapy can aggravate the disease. To this end, the initial patients should adhere to the work and normal activities as much as possible, and exercise as much as they can.