Acroedema?

summary

Acquired angioedema is most common in loose skin, such as eyelids, vulva and lips. It can also be seen in non loose skin, such as hands, feet and extremities. It is characterized by single or multiple sudden localized swelling of the skin with unclear boundary. The skin color is normal or slightly red or pale. It has the feeling of elastic swelling, which lasts for several hours to several days and subsides by itself.

Acroedema?

There is no trace after fading. Wheal often does not appear, conscious symptoms do not itch or mild burning and discomfort, such as involving the nasal mucosa, pharyngeal mucosa, oral mucosa, laryngeal mucosa, can cause runny nose, dyspnea, dysphagia. hoarseness.

Most of the patients with hereditary angioedema developed before the age of 10, and they may have recurrent attacks, even for a lifetime. However, the number of attacks decreased and the severity of the disease decreased after middle age. Although the age of onset is different, it is almost the same in a family. The main manifestation of the patient was localized subcutaneous edema, accompanied by swelling, discomfort and no pruritus. Often occurs in the face or one side of the limb, can also occur in the genitalia. It often occurs singly, and can be accompanied by temporary creeping, annular or reticular erythema. The edema lasts for 1-2 days and subsides spontaneously. In addition to the skin, the mucous membrane may also be involved.

According to the predilection sites, such as eyelids, lips, tongue, earlobes and external genitalia, the sudden asymptomatic swelling subsides spontaneously in a few hours and a few days.

matters needing attention

Hereditary angioedema should be diagnosed if the disease occurs in childhood, and nearly half of the other members of the family have the disease, accompanied by early gastrointestinal and respiratory symptoms, and the serum levels of C1 esterase inhibitor, C2 and C4 are decreased.