How to treat noncompaction of myocardium?

summary

Noncompaction of myocardium (NVM) is a genetic cardiomyopathy characterized by abnormally thick trabeculae and crisscrossed deep crypts. In the past, NVM was not used to treat patients with spongy myocardium, sinus persistent myocardium and embryoid myocardium. It is often called left ventricular noncompaction (LVNC) because it mainly affects the left ventricle. Let's take a look at the following.

How to treat noncompaction of myocardium?

First: drug treatment, cardiotonic, diuretic, vasodilator treatment. B receptor blocker can antagonize cardiac sympathetic nervous system and prevent sudden death. ACEI drugs can prevent ventricular remodeling and improve prognosis by antagonizing RAAS system. Frequent ventricular premature, oral amiodarone treatment, curative effect. Anticoagulant therapy.

Second, NVM combined with other cardiac malformations should be corrected by surgery, and heart transplantation should be performed in patients with progressive heart failure.

Third, pacemaker should be installed in NVM patients with severe bradycardia, including sick sinus syndrome or atrioventricular block of degree Ⅱ or above. ICD should be installed in patients with ventricular tachycardia, especially ventricular fibrillation, to prevent sudden death.

matters needing attention

12% - 50% of NVM patients have family history, and often complicated with heart malformations and other genetic diseases. In recent years, gene variation has been found in many NVM families.