Bone mineral density of lung cancer and symptoms of bone metastasis?

summary

Bone metastasis of lung cancer is a kind of disease with bone damage and pain as the main manifestations, which is caused by some primary malignant tumors outside bone tissue. Breast cancer is the most common cancer with bone metastasis. Breast cancer, lung cancer, kidney cancer, rectal cancer, pancreatic cancer, gastric cancer, colon cancer, ovarian cancer are the most common malignant tumors with bone metastasis, and prostate cancer is the most common primary cancer with bone metastasis. Bone mineral density of lung cancer and symptoms of bone metastasis? I'd like to share my views with you.

Bone mineral density of lung cancer and symptoms of bone metastasis?

After tumor cells arrive at bone marrow with blood flow, they destroy bone tissue by interacting with osteoblasts, osteoclasts and bone stromal cells, release a variety of growth factors stored in bone tissue, and make tumor cells proliferate and form metastatic foci. Bone metastasis can be divided into three types: osteolytic, osteogenic and mixed. Generally speaking, osteolytic metastasis is the main metastasis of breast cancer and lung cancer, while osteogenic metastasis is the main metastasis of prostate cancer.

Bone examination is the most commonly used method, but it is difficult for early diagnosis of bone metastases. In general, only when the bone is damaged more than 1 cm by the cancer, and the bone decalcification reaches 50% - 70%, the X-ray plain film can observe the signs of localized bone mineral density reduction, bone trabecular blur or loss. In the early stage, there are no symptoms. Bone isotope scanning can find the diseased bones in the whole body.

Bone metastases occur in different parts and cause different clinical manifestations, with bone damage and pain as the main manifestations. Chest pain caused by rib metastasis is usually manifested as pain with definite tenderness points and limited chest wall. Spinal cord metastases cause pain in the middle of the back or in the affected area and compression symptoms of the spinal cord, while bone metastases in the limbs or trunk cause localized pain and radiation pain in this area.

matters needing attention

1. The purpose of surgical treatment of bone metastases is to prolong life, relieve symptoms, improve quality of life, prevent or treat pathological fractures, relieve nerve compression, including minimally invasive and vertebroplasty. 2. Extracorporeal radiotherapy is a more traditional treatment, with better analgesic effect, which can effectively prevent paraplegia in patients with severe vertebral bone metastasis, but it has no repair effect on damaged bone.