Allergic clinical symptoms of Rotundine injection?

summary

The indication of Rotundine sulfate injection is analgesia: it is suitable for visceral pain caused by digestive system diseases (such as gastric ulcer and duodenal ulcer pain), general headache, menstrual pain and uterine contraction pain after delivery. Sedation, hypnosis: suitable for patients with tension pain or insomnia caused by pain. Allergic clinical symptoms of Rotundine injection? Let's talk about it

Allergic clinical symptoms of Rotundine injection?

Large dose of this product can inhibit the respiratory center and cause extrapyramidal reaction. In case of overdose, vomiting or gastric lavage can be performed immediately to eliminate the drugs in the stomach. Oxygen inhalation, artificial respiration to relieve respiratory depression, infusion, expansion to improve microcirculation, symptomatic treatment of extrapyramidal system symptoms.

This product has analgesic, sedative, hypnotic and sedative effects. Its analgesic effect is weaker than pethidine and stronger than general antipyretic analgesics. There was no respiratory inhibition or spasm of gastrointestinal smooth muscle in the treatment dose.

It has better effect on chronic persistent pain and visceral dull pain, but less effect on acute sharp pain (such as postoperative pain, traumatic pain, etc.) and advanced cancer pain. At the same time, it can cause sedation and hypnosis. The mechanism of action remains to be elucidated, which may be related to blocking the function of dopamine receptor in brain by inhibiting the ascending activation of brain stem reticular formation. There was no addiction in the amount of treatment.

matters needing attention

1. Although it is a non addictive analgesic, it has a certain tolerance. 2. When it is used for analgesia, it is common for patients to have drowsiness, so it should be used cautiously for drivers, mechanical operators and athletes. 3. It is reported that anaphylactic shock and acute poisoning occurred in this kind of drugs, so it should be paid attention to. When combined with central nervous system inhibitors, the dosage should be adjusted properly if necessary.