Symptoms of intestinal carcinoid?

summary

Intestinal carcinoid is a group of new organisms that occur in the gastrointestinal tract and other organs. Its clinical, histochemical and biochemical characteristics may vary according to its location. The tumor of gastrointestinal carcinoid syndrome can secrete 5-hydroxytryptamine (serotonin), kinin, histamine and other biological active factors, causing vascular dyskinesia, gastrointestinal symptoms, heart and lung lesions, intestinal carcinoid symptoms? Let's talk about it.

Symptoms of intestinal carcinoid?

（1） Local symptoms of gastrointestinal carcinoid syndrome 1. Right lower abdominal pain. Appendiceal carcinoid can cause lumen obstruction, so it often leads to appendicitis, manifested as right lower abdominal pain. 2. Symptoms of intestinal obstruction small intestinal carcinoid and its metastatic mass can cause intestinal obstruction, abdominal pain, abdominal distension, bowel sounds, nausea, vomiting and other symptoms. 3. Abdominal mass may occur in a few carcinoid tumors. Malignant carcinoid tumors invade the surrounding tissues or metastases, often with abdominal mass. 4. Upper gastrointestinal bleeding may occur in gastric or duodenal carcinoid; Intestinal carcinoid can also have hematochezia or occult bleeding, and can cause anemia. 5. Respiratory symptoms the most common manifestation of bronchial carcinoid is respiratory symptoms such as cough, expectoration, hemoptysis, chest pain, etc.

（2） Gastrointestinal symptoms: intestinal peristalsis, can cause paroxysmal abdominal colic, bowel sounds, diarrhea from soft stool to paroxysmal watery stool, etc. Gastrointestinal symptoms were found in 68% - 84% of the patients, most of them had skin paroxysmal flush at the same time, only 15% of the patients had no flush symptoms. A small number of patients may have malabsorption syndrome, causing obvious malnutrition. 2. Respiratory symptoms: gastrointestinal carcinoid syndrome can produce small bronchospasm, causing paroxysmal asthma. 3. Cardiovascular symptoms: after long-term illness, subendocardial fibrosis may occur, affecting the valve part, especially in the right heart, and less in the left heart. Tricuspid insufficiency and pulmonary stenosis are more common in the late clinical stage, which is easy to cause right heart failure. Heart disease is the main cause of death in carcinoid patients. 4. Other symptoms: more than 90% of patients will have liver metastasis, often with signs of hepatomegaly. In the later stage, the joint appeared stiff and painful. X-ray showed that the interphalangeal joint was eroded, most cyst like transparent areas in the phalanx, and osteoporosis in the interphalangeal joint and the proximal joint area of metacarpophalangeal joint.

（3） Clinical symptoms: (1) small intestinal carcinoid should be suspected in patients with right abdominal mass, long-term weight loss and diarrhea; ② The occurrence of intermittent diarrhea, facial telangiectasia, paroxysmal flush, asthma or psychiatric symptoms that can not be explained by other reasons indicates the existence of carcinoid syndrome. If accompanied by hepatomegaly, the possibility of gastrointestinal carcinoid syndrome should be considered; ③ The possibility of colonic carcinoid tumor should be considered in patients with chronic low intestinal obstruction and hematochezia; ④ Young patients with no history of smoking, lung mass, long-term survival, and can exclude other lesions, suggesting that bronchopulmonary carcinoid tumor may be.

matters needing attention

Patients should pay attention to eat more vegetables rich in dietary fiber, such as celery, leek, cabbage, radish, etc. these vegetables rich in dietary fiber can stimulate intestinal peristalsis, increase the frequency of defecation, and take away carcinogenic and toxic substances from feces.