Does pancreatic cancer have familial inheritance

summary

Pancreatic cancer is a highly malignant and poor prognosis tumor. The incidence rate of pancreatic cancer has increased significantly in recent years. Many patients in the clinic ask the same question: will pancreatic cancer be inherited?

Does pancreatic cancer have familial inheritance

First, medical research shows that the vast majority of patients with pancreatic cancer have no family history, but about 10% of the patients have hereditary. Every immediate family member, such as parents and siblings, has pancreatic cancer, and the risk of pancreatic cancer increases by 40%. In collaboration with a family with a history of pancreatic cancer in the northwest of the United States, a research team in the United States has determined that a gene on the long arm of human chromosome 4 can cause pancreatic cancer. 　　

2. However, in clinical practice, Chinese medical circles tend to think that the occurrence of pancreatic cancer is the result of multiple factors. People over 40 years old with the following manifestations need to be highly alert to the possibility of pancreatic cancer: unexplained obstructive jaundice; unexplained weight loss greater than 10%; unexplained upper abdominal or lower back pain; unexplained dyspepsia symptoms; unexplained gastrointestinal symptoms; Sudden diabetes without inducing factors, sudden unexplained fatty diarrhea, spontaneous pancreatitis, etc. 　　

Third, in real life, because pancreatic cancer is too difficult to identify, most patients with pancreatic cancer are found in the middle and advanced stage with metastasis. Although 25% of patients can carry out surgery when they are found, surgery is limited by the location of the pancreas and the surrounding important organs and blood vessels. Even if surgeons can cut down the tree of pancreatic cancer, they can't dig the root below. The 5-year survival rate is only 4.5% - 15%. At present, with the development of radiotherapy technology, modern precise radiotherapy has brought vitality to patients with pancreatic cancer metastasis who have nowhere to seek treatment. The latest international studies have confirmed that the application of volume arc intensity modulated radiotherapy system on the basis of chemotherapy for high-precision and high-dose radiotherapy can prolong the average survival time of patients with advanced pancreatic cancer metastasis, and improve the quality of life of patients to a certain extent, which can also be tolerated by patients with poor physical conditions.

matters needing attention

Diet should be reasonable, pay attention to the proportion of carbohydrate, fat and protein, mainly carbohydrate, the amount of fat and protein should be appropriate, and eat protein suitable for digestion and absorption, such as lean meat, eggs and fish.