Symptoms of cytomegalovirus disease?

summary

A few days ago, the child of one of my colleagues was just born and infected with cytomegalovirus. The child has symptoms of fever, sore throat, headache, body pain, etc. the doctor said: its clinical manifestations are quite similar to infectious mononucleosis caused by EB virus infection, but the heterophilic agglutination test is negative. It sounds really surprising, Can such a small child really be infected with such a serious virus? I don't know if this disease is congenital? Or acquired infection, next I will introduce the symptoms of cytomegalovirus disease

Symptoms of cytomegalovirus disease?

First, the disease is likely to be intrauterine infection, which is one of the important ways of human cytomegalovirus infection. 90% of the infected fetuses are recessive infection, only 10% of them are clinical infection, but sometimes the consequence is more serious.

Second: acquired infection of cytomegalovirus in infants, mostly recessive infection or mild symptoms, but a few patients with more serious clinical manifestations, perinatal infection of neonatal patients, some of which may be intrauterine infection, can be persistent pneumonia, children and adult patients can develop cytomegalovirus hepatitis.

Third: at present, there is no mature antiviral drugs for this disease. Ganciclovir and foscarnet sodium are two antiviral drugs for the treatment of CMV infection. They have been used in the treatment of AIDS patients, patients with CMV infection after organ transplantation, or preventive drugs after organ transplantation, but the effect is not very ideal after clinical use.

matters needing attention

Cytomegalovirus mainly invades epithelial cells. The main organs (lung, liver, brain, kidney, spleen, heart, intestine), glands (salivary gland, gonad) and nervous system can be involved. The infected cells degenerated, increased in size, presented as giant cells, and then disintegrated, leading to local necrosis and inflammation.