How is spontaneous abortion caused?

summary

The causes of spontaneous abortion are complex and varied. The common causes of early abortion are chromosome abnormality, endocrine abnormality, uterine dysplasia or malformation. Here are a few reasons in detail, hoping to help the father or mother to be.

How is spontaneous abortion caused?

Chromosome abnormalities include chromosome number abnormalities, such as monosomy, trisomy and polyploidy; Structural abnormalities, such as breakage, deletion and translocation, can lead to abortion. It was found that 60% of spontaneous abortion had abnormal karyotype. The abnormal karyotype is accompanied by a structural abnormality of fetus or placenta. The normal karyotype of abortion fetus is more normal.

Endocrine disorders, excessive estrogen and progesterone deficiency are also the causes of early abortion. At 12-14 weeks of gestation, the placental formation is replacing the luteal function of pregnancy. In addition, the lack of thyroxine, so that the oxidation process of cells suffer obstacles, as well as hyperthyroidism and diabetes are prone to abortion.

Placental abnormalities and placental endocrine deficiency. Decidualitis in early pregnancy can cause hemorrhage or hyperplasia of the basal decidua, dissolution of villous epithelial cells and decidual cells, vascular obstruction in the villi, affecting the absorption and delivery of nutrients, resulting in the separation of pregnant eggs from the attachment, bleeding and abortion. In addition, if there is a huge infarction in the placenta, the function of the placenta will decrease and the survival of the fetus will be affected; And placenta previa, placenta villi edema degeneration caused abortion is not uncommon. In maternal blood after pregnancy β- HCG, HPL, P, E2, estrone, if these hormone values decrease in early pregnancy, 50% of abortion.

matters needing attention

Due to previous pregnancy or blood transfusion, Rh factor and incompatible ABO blood group factor produced antibodies in the mother. In this pregnancy, the placenta entered the fetus and agglutinated with red blood cells to produce hemolysis, resulting in abortion. Mental and neurological factors such as fright and severe mental stimulation can also lead to abortion. In recent years, studies have shown that noise and vibration have certain effects on human reproduction.