Symptoms of immunodeficiency syndrome?

summary

Immunodeficiency disease (IDD) is a group of diseases caused by immune deficiency due to immune system hypoplasia or damage. There are two types: 1. Primary immunodeficiency, also known as congenital immunodeficiency, is related to heredity and occurs mostly in infants. ② Secondary immunodeficiency disease, also known as acquired immunodeficiency disease, can occur at any age. It is mainly caused by severe infection, especially infection that directly invades the immune system, malignant tumor, application of immunosuppressants, radiotherapy and chemotherapy. Symptoms of immunodeficiency syndrome? Let's talk about it

Symptoms of immunodeficiency syndrome?

Increased susceptibility to various infections is the most important, common and serious manifestation and consequence of immunodeficiency, and infection is also the main cause of death. The younger the patient is, the higher the infection frequency is and the more serious the disease is. Infection may be recurrent or persistent, acute or chronic. There was no obvious gap between the two infections. The most common site of infection was respiratory tract.

The nature of infection mainly depends on the type of immune deficiency, such as humoral immunity, phagocytosis and complement deficiency. The infection is mainly caused by suppurative cells such as Staphylococcus, Streptococcus and pneumococcus. The clinical manifestations are tracheitis, pneumonia, otitis media, suppurative meningotis and pyoderma. The infection of cellular immunodeficiency is mainly caused by viruses, fungi, intracellular parasites and protozoa.

People with immunodeficiency are susceptible to normal flora and non pathogenic or weak pathogenic microorganisms in air, soil and water, such as Escherichia coli, Pseudomonas aeruginosa and Proteus. This type of infection is called opportunistic infection. Most primary immunodeficiency diseases have genetic tendency, about 1 / 3 of them are autosomal, 1 / 5 are recessive.

matters needing attention

① Protective isolation of patients, reduce contact with the source of infection; ② Patients with immunodeficiency should not be vaccinated with live vaccine to prevent severe vaccine infection; ③ Generally, tonsillectomy and lymphadenectomy are not performed. Splenectomy is contraindicated. Immunosuppressive drugs should be used with caution; ④ Antibiotics were used to eliminate bacterial and fungal infections; ⑤ According to the type of immune deficiency, replacement therapy or immune reconstitution were given.