What is mandatory spondylitis

Update Date: 2024-04-16 Source: Network

summary

Ankylosing spondylitis is a relatively high incidence in recent two years, which often leads to people's weakness. Next, I would like to share with you what kind of disease ankylosing spondylitis is.

What is mandatory spondylitis

First of all, genetic factors play an important role in the pathogenesis of as. According to epidemiological investigation, the positive rate of HLA-B27 in as patients is as high as 90% - 96%, while the positive rate of HLA-B27 in general population is only 4% - 9%; The incidence rate of AS in HLA-B27 positive patients was about 10% to 20%, while the incidence of common people was 1 to 2 per cent, which was about 100 times higher than that in the general population. It was reported that the risk of AS in AS group was 20~40 times higher than that in the general population. The prevalence rate of AS first degree relatives was 24.2%, which was 120 times higher than that of the normal population. The probability of AS occurrence in relatives of HLA-B27 positive healthy persons was far lower than that of HLA-B27 positive AS patients. These results indicate that HLA-B27 is an important factor in the pathogenesis of as.

Secondly, suffering from ankylosing spondylitis will lead to swelling of our joints, and our usual actions are not particularly flexible.

Finally, methotrexate: active ankylosing spondylitis patients after sulfasalazine and non steroidal anti-inflammatory drugs treatment invalid, can use methotrexate. However, through comparative observation, it was found that the product could only improve the symptoms of peripheral arthritis, low back pain, stiffness, iritis, and the levels of ESR and CRP, but had no evidence to improve the radiation lesions of the central axis joint.

matters needing attention

After suffering from ankylosing spondylitis, we must not engage in heavy physical labor. We should often rest in bed, pay attention to our work and rest habits, go to bed early and get up early. We can often go outdoors to do some simple exercises to improve our physique.