Why is myasthenia gravis serious

Update Date: Source: Network

summary

About five months later, the patient couldn't lift a foot when he went up the stairs. He had no strength. He felt heavy, but he didn't feel good. He went to the hospital for examination. The doctor said it was myasthenia gravis. After treatment, he got better. Now let's share the reason why the left side of myasthenia gravis is serious.

Why is myasthenia gravis serious

Treatment 1: myasthenia gravis is an autoimmune disease, cholinesterase inhibitors, glucocorticoids, immunoglobulin are commonly used in the treatment of drugs, related studies show that the use of glucocorticoid prednisone oral combined with intravenous immunoglobulin treatment of myasthenia gravis better.

Treatment 2: glucocorticoid has a wide range of regulatory effects on the immune system, and has become one of the main treatment methods in traditional treatment. However, long-term large-scale use of hormone has serious adverse reactions, especially in myasthenia gravis crisis, short-term high-dose pulse therapy can inhibit the release of presynaptic membrane acetylcholine, which may lead to the aggravation of myasthenia gravis. When respiratory muscle paralysis occurs, ventilator should be used.

Treatment 3: immunoglobulin can provide a large number of idiotypic antibodies, which can neutralize pathological autoantibodies and prevent them from acting on autoantigens; at the same time, it can reduce the production of autoantibodies; accelerate the degradation and metabolism of IgG antibodies; inhibit pathological cytokines; regulate the function of T cells and neutralize super antibodies, so as to reduce toxic T cells; and; It can compete or inhibit the binding of antibody circulating immune complex with autoantigen and enhance the inactivation of circulating immune complex. Nicotinic acetylcholine receptor (nAChR) is the antigen that causes autoimmune response in myasthenia gravis. Intravenous immunoglobulin therapy not only improves the clinical symptoms of myasthenia gravis, but also significantly reduces the blood titer of patients after treatment.

matters needing attention

Warm reminder: the surgical treatment is thymus or thymoma resection, but the effect of surgical treatment is not optimistic, at the same time, there are also some patients after the operation time is not long, is likely to have the possibility of recurrence, and more serious than before the operation. Eat more fruits and vegetables, ensure the balance of nutrition, according to their own condition, pay attention to digestion when eating; reasonable diet, maintain adequate nutrition, strengthen the physique. In different stages of the disease to make dietary care grading, but also to protect the nutritional balance of patients.