Nail visible horizontal groove spinning what reason?

summary

Both infants and children can suffer from this disease. There is no obvious seasonality, or more in summer. The vast majority of children with good prognosis, a self limiting process, appropriate treatment can gradually recover. This is very different from infantile nodular periarteritis. Nail visible horizontal groove spinning what reason? Let's talk about it

Nail visible horizontal groove spinning what reason?

The etiology has not been fully elucidated. Rickettsia and Propionibacterium acnes, which were suspected to be transmitted by dust mites, were the causes of the disease, but they were not confirmed; It has also been reported to be related to retroviruses,

Reverse transcriptase activity associated with retrovirus was found in peripheral blood mononuclear cells of patients. Japanese studies found that the frequency of hla-bwzz in patients was about 2 times higher than that in the general population; However, the detection rate of hla-bw increased in Boston area. Therefore, genetic susceptibility and infection may be the cause of the disease.

In the acute stage of Kawasaki disease, T lymphocytes decreased, circulating T4 cells activated, T8 cells decreased and B lymphocytes activated. These immune abnormalities may be caused by lymphotropic tissue virus infection, and the affinity of the virus to endothelial cells may be the cause of multiple vasculitis.

matters needing attention

Corticosteroids have always been considered to have a strong anti-inflammatory effect and relieve symptoms. However, it was found that corticosteroids are easy to cause thrombosis, hinder the repair of coronary artery lesions and promote the formation of aneurysms. Therefore, corticosteroids such as prednisone should not be used alone.