Why is pancreatic cancer easy to relapse

summary

One year ago, pancreatic cancer was found in the tail of the pancreas. The size of the tumor is 5cm. The main symptoms are red urine, mental fatigue, abdominal pain, anorexia, rib pain. Chemotherapy has been carried out for more than ten times. Now the pancreatic tumor has spread, involving the spleen and stomach, and is diagnosed as advanced pancreatic cancer. Now let's talk about why pancreatic cancer is easy to relapse.

Why is pancreatic cancer easy to relapse

First, the risk of postoperative recurrence is relatively high. Most patients with pancreatic cancer are weak and have low immunity,

Second, only 10% - 20% of the patients can have radical resection. Even if the patients have radical resection, about 50% - 70% of them will have recurrence within one year. The 5-year survival rate of pancreatic cancer has been lower than 5% in recent 20 years. The 5-year survival rate of patients with advanced pancreatic cancer is less than 1%, and the prognosis is very poor. Therefore, pancreatic cancer is known as "the king of cancer".

Third, clinical studies have found that peripancreatic retroperitoneal nerve invasion is an important risk factor for recurrence and survival of pancreatic cancer. At present, about 50% of the retroperitoneal margin of pancreatic head cancer has not reached the negative margin, that is, the invaded nerve and soft tissue has not been completely cleaned. The residual cancer cells in the retroperitoneal nerve tissue around the pancreas may be an important reason for the recurrence of pancreatic cancer and affect the long-term survival.

matters needing attention

It is expected to improve the postoperative survival of patients with pancreatic cancer by standardized radical dissection of the nerve plexus in the 5 groups of peripancreatic retroperitoneum.