What is eyelid opening and eyelid closing dysfunction?

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What is eyelid opening and eyelid closing dysfunction? Apraxia of eyelid opening and closing: involuntary inhibition of levator palpebrae and orbicularis oculi. It is one of the typical signs of Parkinson's disease in the elderly. Let's understand the symptoms of the disease and follow-up treatment, hoping to help you.

What is eyelid opening and eyelid closing dysfunction?

Typical signs: ① striatal hand: flexion of metacarpophalangeal joint, extension of proximal interphalangeal joint and flexion of distal interphalangeal joint; At the same time, foot deformity can also occur. ② Myerson's disease: tapping out the bridge of the nose or between the eyebrows does not inhibit blink reaction. ③ Oculomotor crisis: ankylosing spasm of gazing between two eyeballs. It is common for two eyeballs to look up, but rare for side and down. It occurs repeatedly and is often combined with neck, mouth and muscle spasm. ④ Apraxia of eyelid opening and closing: involuntary inhibition of levator palpebrae and orbicularis oculi.

Atypical signs: the knee reflexes vary greatly, can be normal, difficult to elicit, and can also be active. It is only limited to PD patients with single measurement. The bilateral knee reflexes are symmetrical and flexing reflexes, and the lower frontal reflex and frontal reflex rarely increase. The diagnosis of typical tremor paralysis is not difficult. According to the typical tremor, ankylosis, reduced movement and other symptoms, combined with rubbing ball like movement, lead tube or gear like myotonia, mask face, lower case syndrome, flustered gait and other signs, the diagnosis can be made generally.

Some drugs, such as phenothiazines, can block the synaptic transmission of dopamine and cause tremor, rigidity and other symptoms. In addition, reserpine can block the storage of dopamine at the end of axons, and the metabolites of methyldopa can compete for dopamine receptors. These drugs can produce symptoms of tremor paralysis syndrome. The history of taking medicine and the recovery of symptoms can be identified.

matters needing attention

Parkinson's disease is a progressive degenerative disease. All drug treatments can only improve the quality of life and work of patients, but can not prevent the development of the disease. Patients will eventually lose their ability to live. From the symptoms, tremor is the main cause of Parkinson's disease, and the prognosis is better, while the elderly people are less active, so the prognosis is poor. The disability rate is 25% in 1-5 years, 66% in 6-9 years, and 80% in 10-14 years. The main causes of death of Parkinson's disease are late complications caused by less active, such as bedsore, sepsis, heart failure, pulmonary infection and urinary tract infection, They account for 50%, 28%, 14% and 8% of the causes of death in Parkinson's disease, respectively. Most patients with Parkinson's disease die in the early morning because of the weakening of parasympathetic excitation and the effect of levodopa.