The effect of magnesium sulfate poisoning symptoms of pregnant women?

Update Date: Source: Network

summary

Magnesium sulfate, or anhydrous magnesium sulfate and magnesium sulfate heptahydrate, is a compound containing magnesium with the molecular formula of MgSO4 (or MgSO4 · 7H2O). Anhydrous magnesium sulfate is a common chemical reagent and drying reagent. However, magnesium sulfate often refers to magnesium sulfate heptahydrate, because it is not easy to dissolve, it is easier to weigh than anhydrous magnesium sulfate, which is convenient for quantitative control in industry. The effect of magnesium sulfate poisoning symptoms of pregnant women? Now let's give you a detailed introduction.

The effect of magnesium sulfate poisoning symptoms of pregnant women?

Intravenous injection of magnesium sulfate often causes hot flashes, sweating, dry mouth and other symptoms, rapid intravenous injection can cause nausea, vomiting, panic, dizziness, individual nystagmus, slow down the injection speed, symptoms can disappear.

When the concentration of blood magnesium reaches 5mmol / L, the muscle excitability is inhibited, the sensory response is slow, the knee tendon reflex disappears, and the respiration begins to be inhibited. When the concentration of blood magnesium reaches 6mmol / L, the respiratory arrest and arrhythmia occur, and the heart conduction block occurs. When the concentration of blood magnesium further increases, the heartbeat stops.

Continuous use of magnesium sulfate can cause constipation, and some patients may have paralytic ileus, which will be improved after drug withdrawal. In a few cases, the blood calcium decreased and hypocalcemia reappeared. Magnesium ion can freely pass through the placenta, resulting in neonatal hypermagnesemia, which is characterized by low muscle tension, poor sucking power, inactivity, poor crying, and a few respiratory depression. A few pregnant women had pulmonary edema.

matters needing attention

During catharsis, if you take a large amount of high concentration solution, you may absorb a large amount of water from the tissue and lead to dehydration; Because intravenous injection is more dangerous, it should be mastered by experienced doctors. The injection should be slow, and attention should be paid to the patient's breathing and blood pressure. In case of poisoning (such as respiratory muscle paralysis), 10ml 10% calcium gluconate injection can be injected intravenously for rescue; It is forbidden for patients with intestinal bleeding, acute abdomen, pregnant women and menstrual women; It is not suitable to use this product for catharsis in order to avoid aggravating central inhibition.