What does the medicine of nasopharyngeal carcinoma chemotherapy have

summary

My neighbor's aunt is over sixty years old. Because she works in the factory all the year round, she suffers from nasopharyngeal carcinoma. My aunt has been receiving chemotherapy. She thinks the drugs in the local hospital are a little expensive. She wants to send some back to her children who work in other places. My aunt asked me to inquire about the chemotherapy drugs for nasopharyngeal carcinoma. Now let me talk about the radiotherapy drugs for nasopharyngeal carcinoma.

What does the medicine of nasopharyngeal carcinoma chemotherapy have

First, the complex of bleomycin and iron is embedded into DNA, causing single and double strand breaks. It does not cause RNA strand breaks. The first step is that the dithiocao ring of the product is embedded between the G-C base pairs of the DNA, and the positive charge of the terminal tripeptide amino acid interacts with the DNA phosphate group to make it break the chain. The second step of the action is that the complex of the product and iron leads to the formation of superoxide or hydroxyl radicals, causing DNA strand breaks.

Second, 5-FU is the first antimetabolic drug synthesized according to certain assumptions, and it is the most widely used anti pyrimidine drug in clinic. It has good curative effect on gastrointestinal cancer and other entities, and plays an important role in the treatment of tumor internal medicine. 5-fluorouracil has antitumor activity. 5-FU inhibits DNA synthesis by inhibiting thymidine nucleotide synthase. This enzyme may transfer one carbon unit of formyltetrahydrofolate to deoxyuridine phosphate to synthesize thymine nucleic acid monoacid. 5-FU also inhibited the synthesis of RNA.

Third: cisplatin has the characteristics of broad anti-cancer spectrum, strong effect, synergistic effect with a variety of anti-tumor drugs, and no cross resistance. It is one of the most commonly used drugs in the current combined chemotherapy. In addition to the common chemotherapy drugs, the more commonly used drugs are combined with traditional Chinese medicine, such as the combination with modern anti-cancer traditional Chinese medicine chlorhexidine, which can play the role of traditional Chinese medicine and Western medicine, with good effect More obvious. Cisplatin is a heavy metal complex with two chlorine atoms and two ammonia molecules, which is similar to bifunctional alkylating agent and can replicate with DNA. DDP cells were the most sensitive and inhibited RNA and protein synthesis at high concentration.

matters needing attention

Nasopharyngeal carcinoma patients should have a specific understanding of their condition before medication, and at the same time, they should make clear the symptoms suitable for the drug, and then choose the drug. They should not blindly use the drug, which will bring great burden to the body. It is best to consult the doctor first, maintain a good attitude, and adhere to the treatment, so as to have great effect.