How is leukaemia kidney damage to return a responsibility?

summary

Leukemia can cause kidney damage, mostly by direct infiltration of leukemia cells or by metabolites. It can also damage the kidney through immune response and electrolyte disorder, manifested as acute renal failure, chronic renal failure, nephritis syndrome and nephrotic syndrome. How is leukaemia kidney damage to return a responsibility? Let's talk about it

How is leukaemia kidney damage to return a responsibility?

The renal damage of leukemia cells may be related to the fact that the embryonic kidney is also a hematopoietic tissue. Acute leukemia is the most common cause of renal infiltration. Acute monocytic leukemia and acute lymphocytic leukemia are more likely to infiltrate the kidney. Leukemic cells often infiltrate directly into the kidney, including renal parenchyma, renal interstitium, renal vessels, perirenal tissues and urinary tract.

Leukemic cell infiltration leukemic cells often directly infiltrate the kidney, which can infiltrate renal parenchyma, renal interstitium, renal vessels, perirenal tissues and urinary tract. The high incidence of renal infiltration may be related to the fact that the embryonic kidney is also a hematopoietic tissue. Acute leukemia is the most common cause of renal infiltration. Acute monocytic leukemia and acute lymphocytic leukemia are more likely to infiltrate the kidney.

Immunoreactive chronic lymphocytic leukemia can be complicated with immune complex nephritis. The fibrillar SUBMICROSTRUCTURE can be found under electron microscope. The fibrillar deposit is an immune complex composed of IgG and anti IgG antibody. In addition, cellular immunity is also possible.

matters needing attention

In order to prevent uric acid nephropathy, dehydration and acidic urine should be avoided. Allopurinol should be used at least three days before chemotherapy to control blood uric acid and urine acid in normal range; During chemotherapy, fluid should be added and urine should be alkalized to maintain the pH of urine between 6.2 and 6.8. In addition to allopurinol, basic drugs and rehydration should be added to reduce uric acid deposition when uric acid nephropathy has occurred.