How does neonatal hepatitis do?
summary
The primary goal of neonatal hepatitis treatment is complete remission of symptoms, but in life, many people are not very aware of this early symptoms, and when the disease has been quite serious. Complete improvement of Biochemistry and liver histology; The ultimate goal is to maintain sustained remission without medication. In order to avoid this situation, let's talk about how to do neonatal hepatitis?.
How does neonatal hepatitis do?
First: ursodeoxycholic acid (UDCA): it can relieve fatigue, diarrhea, pruritus and other symptoms of patients, maintain the stability of cell membrane, reduce inflammation of hepatocytes, improve liver function, increase carbonate secretion of bile capillaries, promote bile secretion, increase bile flow, and promote jaundice regression. 500 mg per day, divided oral, no obvious side effects. Recently, it has been suggested that UDCA can be used as an additional treatment for chronic hepatitis C with IFN.
Second: phenobarbital: as an enzyme inducer, it can induce the production of Y protein, enhance its activity, promote the transformation of bilirubin from non binding to binding, improve the enzyme activity of hepatic smooth endoplasmic reticulum and Na-K-ATPase activity on bile capillary membrane, promote bile acid secretion, increase bile flow, so as to promote cholangitis and jaundice. 90-180 mg per day. This medicine has certain damage to the liver. If the liver function changes obviously, it should be used with caution. If there are side effects such as fatigue, drowsiness and rash, it should be observed.
Third: adrenocortical hormone: with non-specific anti-inflammatory effect, can increase bile flow, promote bile excretion, thus has the effect of jaundice. The dosage of prednisolone was 40 mg per day. The dosage was gradually reduced after 5-7 days. The course of treatment was about 1 month. We should pay close attention to the occurrence of adverse reactions and use them cautiously.
matters needing attention
In terms of diet, specific dietary guidance should be given to the patients according to the situation of each disease. For example, when the renal function is not complete, the patients should take high calorie (mainly sugar), high-quality low protein diet, limited fluid intake and maintain water balance.
