Nephrotic syndrome renal vein thrombosis symptoms?

summary

In nephrotic syndrome, it is often caused by fire. When plasma albumin is less than 2.0g/d1, the risk of renal vein thrombosis increases. Most of them think that the thrombus first formed in the venules, then extended and finally involved the renal veins. Is there a patient with nephrotic syndrome presenting with renal vein thrombosis?, Today I'd like to share this with you.

Nephrotic syndrome renal vein thrombosis symptoms?

First, renal vein thrombosis, in patients with membranous nephropathy can be as high as 50%, in other pathological types, the incidence is 5% - 16%. Acute renal vein thrombosis patients can be manifested as sudden onset of low back pain, hematuria, leukocyturia, increased urine protein and renal dysfunction.

Second: chronic type patients have no symptoms, but renal blood stasis after thrombosis often aggravates proteinuria, or has poor response to treatment. Because thrombus falls off, the symptom of extrarenal embolism is common, and pulmonary embolism may occur. It can also be accompanied by renal tubular dysfunction, such as diabetes, amino acid urine and renal tubular acidosis. Renal venography is necessary for definite diagnosis. Doppler ultrasound, CT, IMR and other non-invasive examinations are also helpful in the diagnosis.

Third: plasma β The increase of thrombus protein indicates potential thrombosis, and the increase of thrombus protein in the blood may lead to the formation of thrombus α The increase of 2-antifibrinolytic enzyme is also considered as a marker of renal vein thrombosis. Peripheral deep vein thrombosis rate is about 6%. It is common in deep vein of leg. Only 12% of patients have clinical symptoms, and 25% can be found by Doppler ultrasound. The incidence of pulmonary embolism was 7%, and 12% had no clinical symptoms. Other venous involvement is rare. Arterial thrombosis is more rare, but in children, although the incidence of thrombosis is quite low, arterial and venous involvement is as common.

matters needing attention

1. The daily total calorie intake should be controlled by diet therapy. The calorie produced by fat intake should be less than 20% ~ 30% of the total calorie intake. The daily cholesterol intake should be less than 150 ~ 300 Mg2 when unsaturated / saturated ≥ 1. HMG CoA reductase inhibitors (statins): cholesterol lowering beta: triglyceride lowering. For example, antinomine, clofibric bile acid binding resin: binding bile acid, promoting cholesterol conversion, bile acid probucol: mild cholesterol lowering, vitamin E3, blood purification treatment, separation of LDL2 / W × 3w