What are the drugs for Parkinson's disease
summary
Years of limb shaking, walking inconvenience, muscle stiffness are the usual symptoms of Parkinson's disease patients. What bothers them most is the endless shaking of their hands, which makes them unable to complete their normal life and work. What are the drugs for Parkinson's disease? Let's get to know.
What are the drugs for Parkinson's disease
First, dopamine can be oxidized and degraded by MAO-B in the brain, and a large number of oxygen free radicals can be produced in the process of dopamine metabolism, which can damage neurons. In addition, MPTP is oxidized to toxic MPP + through mao-b. therefore, inhibiting the activity of MAO-B can not only prolong the residence time of dopamine in the brain, enhance the curative effect, reduce the dosage of levodopa and its side effects, but also indirectly protect neurons. Commonly used drugs are midopipide (selegiline) and strychnine.
Second, it is a common way to supplement dopamine in the brain for Parkinson's patients, and the commonly used drugs are Madopar and pajinning controlled release tablets.
Third, ergot receptor agonists (olfactory cryptic arrest and xielangxing) are rarely used due to the risk of pulmonary and cardiac valve fibrosis. Non ergot receptor agonists are recommended, including telsuda and senfro.
matters needing attention
Parkinson's disease treatment, treatment of Parkinson's disease is not a single method, but we must pay attention to the focus of treatment, this is very important for patients with Parkinson's disease, in addition, we should also in daily life, appropriate self-care, for example, we should pay attention to physical movement.