How to treat ABO hemolysis

Update Date: Source: Network

summary

ABO hemolysis is also a common disease, which will not happen under normal circumstances. If the mother to be is type O blood, we should pay attention to this problem. If there is, we should not worry too much, and we should treat it in time. Let's talk about how to treat ABO hemolysis.

How to treat ABO hemolysis

First: comprehensive therapy, in order to improve the fetal resistance and bilirubin metabolism ability, 10 days of comprehensive therapy were given at 24 weeks, 30 weeks and 33 weeks of gestation respectively. The methods were as follows: intravenous injection of 50% glucose 40 mg and vitamin C 100 mg daily; oxygen inhalation, 2-3 times a day, 15-20 minutes each time, vitamin E 30 mg, 3 times a day. If necessary, the treatment time can be prolonged and the course of treatment can be increased. Oral administration of phenobarbital 10-30mg 2-3 times a day for about 2 weeks before delivery can enhance the activity of glucuronosyltransferase in fetal liver cells, enhance bilirubin metabolism and reduce the incidence of nuclear jaundice. Yinchenhao Decoction (Yinchenhao 9g, zhidahuang 4.5g, Huangqin 9g, Gancao 6g) was decocted once a day until delivery.

The second is the treatment during production. Strive for natural childbirth, avoid the use of sedatives, anesthetics, so as not to increase the chance of fetal asphyxia. Prepare for neonatal rescue. The umbilical cord should be cut off immediately after delivery to reduce the antibody entering the body of the baby, and the umbilical cord should be kept about 10 cm long for medication or exchange transfusion when necessary. Immediately after birth, 25% glucose 10ml, vitamin C 100mg, nicothamide 125mg and / or hydrocortisone 25mg were injected into the umbilical vein. The blood group, bilirubin, special antibody, red blood cell, hemoglobin and nucleated red blood cell were detected.

Third: neonatal treatment. On the first day to the second day of life, mild patients should pay attention to the time of jaundice, the speed and degree of aggravation. If anemia is serious at birth and cord blood hemoglobin is less than 12g%, blood transfusion should be considered; 2-7 days, the key point is to prevent nuclear jaundice caused by hyperbilirubinemia, the degree and speed of serum indirect bilirubin increase should be closely monitored, so as not to exceed the critical concentration of nuclear jaundice (18-20mg%); within 2 months after delivery, attention should be paid to the anemia caused by red blood cell regeneration dysfunction Blood, transfusion if necessary.

matters needing attention

The above is the summary of several ABO hemolysis treatment, if this happens, to timely inspection and treatment, so as to minimize the impact on the mother and baby.