With what medicine is neonate low blood phosphorus good?

summary

Hypophosphatemic vitamin D-resistant rickets is a kind of deficiency disease. Its pathogenesis is due to renal tubular defect. The kidney loses phosphorus, which leads to the metabolic disorder of calcium and phosphorus. Generally speaking, it has no response to vitamin D. This disease is most common in children close to one year old, most often O-shaped legs and X-shaped legs, serious even can not walk normally, and accompanied by serious deformities, physical development is greatly affected. Such patients are often accompanied by tooth pain, tooth loss, or backward, not easy to grow, low blood phosphorus. Let's share my experience with you.

With what medicine is neonate low blood phosphorus good?

The diagnosis of this kind of disease is mainly based on low blood phosphorus. Under normal circumstances, the serum phosphorus value decreased by 0.48-0.97 mmol / L, at most about 0.65 mmol / L, showing normal or slightly decreased blood calcium value, serum alkaline phosphatase activity increased significantly, even in the presence of hypophosphatemia, but urinary phosphorus excretion is still increasing.

The focus of treatment for these patients is to prevent bone growth deformity, need to improve blood phosphorus, maintain at about 0.97 mmol / L, which is good for bone calcification, and at the same time maintain normal growth rate, try to avoid vitamin D poisoning caused by high urine calcium, high blood calcium and other similar conditions.

Generally speaking, the dosage of vitamin D2 is 50000-200000 u within 24 hours. Vitamin D is extremely easy to accumulate in the body fat, accumulated to a certain amount before it is easy to be found poisoning symptoms, so we should pay attention to it.

matters needing attention

This kind of disease is a congenital disease. During pregnancy, pregnant women should keep away from smoke, radiation, alcohol, pesticides, noise and other harmful gases and toxic metals, and prevent infection during this period, so as to achieve regular inspection. And firmly prohibit close relatives marriage.