Routine medication for myasthenia gravis

summary

The key to cure the disease is to regulate the number of AChR, dissolve the deposition of postsynaptic membrane and inhibit the production of anti AChR antibody. Then there are patients with myasthenia gravis routine medication.

Routine medication for myasthenia gravis

Treatment 1: myasthenia gravis is an autoimmune disease, cholinesterase inhibitors, glucocorticoids, immunoglobulin are commonly used in the treatment of drugs, related studies show that the use of glucocorticoid prednisone oral combined with intravenous immunoglobulin treatment of myasthenia gravis better.

Treatment 2: glucocorticoid has a wide range of regulatory effects on the immune system, and has become one of the main treatment methods in traditional treatment. However, long-term large-scale use of hormone has serious adverse reactions, especially in myasthenia gravis crisis, short-term high-dose pulse therapy can inhibit the release of presynaptic membrane acetylcholine, which may lead to the aggravation of myasthenia gravis. When respiratory muscle paralysis occurs, ventilator should be used.

Treatment 3: immunoglobulin can provide a large number of idiotypic antibodies, which can neutralize pathological autoantibodies and prevent them from acting on autoantigens; at the same time, it can reduce the production of autoantibodies; accelerate the degradation and metabolism of IgG antibodies; inhibit pathological cytokines; regulate the function of T cells and neutralize super antibodies, so as to reduce toxic T cells; and; It can compete or inhibit the binding of antibody circulating immune complex with autoantigen and enhance the inactivation of circulating immune complex. Nicotinic acetylcholine receptor (nAChR) is the antigen that causes autoimmune response in myasthenia gravis. Intravenous immunoglobulin therapy not only improves the clinical symptoms of myasthenia gravis, but also significantly reduces the blood titer of patients after treatment.

matters needing attention

This disease needs attention: life should be regular, in terms of diet should eat more high protein foods, such as: chicken, duck, fish, lean meat and fresh fruits and vegetables, nutrition collocation is very important for patients. We should pay attention to all kinds of infection and the digestibility of food.