What is the cause of general epilepsy

summary

In our daily life, we must pay attention to the onset of epilepsy, the seizure of epilepsy, caused great trouble to patients, we should be very clear in our hearts, and even had an impact on their work. Epilepsy Hospital experts told us that only when we know the cause of epilepsy, can we prevent epilepsy, and for the prevention and treatment of epileptic seizures, we should also understand the causes of epileptic seizures.

What is the cause of general epilepsy

Reason 1: acquired factors: structural or metabolic abnormalities of the brain caused by acquired factors can produce epileptogenic foci or reduce the seizure threshold. The lesions can be localized or diffuse, static or progressive. This kind of temporal lobe epilepsy is called secondary (or secondary) temporal lobe epilepsy. Genetic factors may also play an important role in secondary temporal lobe epilepsy, especially in childhood.

Reason 2: brain injury: including open brain injury and closed brain injury. According to statistics, about one third of patients with temporal lobe epilepsy have a history of head injury. There is no doubt that brain injury is one of the main causes of temporal lobe epilepsy. Patients with temporal lobe epilepsy after brain injury is still a small number, about 5% of patients with temporal lobe epilepsy after brain injury, but after brain injury, patients with temporal lobe epilepsy in the early stage may be a quarter of patients with temporal lobe epilepsy in the late stage. Extrabrain injury during childbirth is an important cause of temporal lobe epilepsy in children.

Reason 3: genetic factors: refers to the genetic susceptibility to temporal lobe epilepsy. A large number of studies have proved that temporal lobe epilepsy is related to genetic factors. Heredity can affect the function of ion channels in cell membrane, reduce convulsion threshold and cause neuronal discharge. The study of coincidence rate of twin temporal lobe epilepsy and the study of family electroencephalogram suggest that the quality of temporal lobe epilepsy is autosomal dominant inheritance, and the penetrance rate is high between 5 and 15 years old.

matters needing attention

The main causes of temporal lobe epilepsy are different in different ages. Age and brain maturity affect not only the tendency of seizure, but also the type of seizure. The etiology and age distribution of temporal lobe epilepsy in children have guiding significance for the diagnosis and prevention of temporal lobe epilepsy. We must pay enough attention to the brain development, genetics, metabolism, midwifery technology and other issues in perinatal period, neonatal period and infantile period.