Symptoms of intrauterine infection during pregnancy?

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Intrauterine infection, also known as congenital infection or mother to child transmission disease, refers to the intrauterine infection of the fetus caused by infection during pregnancy. The main route of intrauterine infection is vertical transmission of pathogenic microorganism to fetus through placenta; The retrograde diffusion of pathogenic microorganisms in the lower genital tract of pregnant women; Perinatal infection during delivery. Symptoms of intrauterine infection during pregnancy? Let's talk about it.

Symptoms of intrauterine infection during pregnancy?

The influence of intrauterine infection on the fetus is a complex problem, which is related to the gestational age at the time of infection, the immune status of pregnant women, the types of pathogenic microorganisms and the severity of infection. It is generally believed that the infection in early pregnancy is more serious, because this period is the sensitive stage of fetal organ development. Therefore, it is very important for pregnant women to prevent infection in early pregnancy to protect the health of their offspring.

Intrauterine infection can lead to abortion, congenital malformation (including congenital disability), stillbirth and so on. However, different pathogenic microorganisms have different characteristics of fetal injury: herpesvirus infection mainly damages the fetal central nervous system, causing microcephaly, brain hypoplasia, etc; Congenital cataract is a typical feature of rubella virus infection; Coxsackievirus infection often causes congenital heart disease, such as patent ductus arteriosus, ventricular septal defect, etc; One consequence of congenital cytomegalovirus infection is neonatal hepatitis syndrome.

Intrauterine infection in early pregnancy is an important measure to prevent mother to child transmission of diseases, but this kind of infection often has no obvious clinical symptoms and is difficult to diagnose. Therefore, the diagnosis of intrauterine infection mainly depends on laboratory diagnostic technology. At present, diagnostic reagents for rubella, Toxoplasma gondii and cytomegalovirus have been sold in China. Some areas have gradually taken intrauterine infection and screening as the content of pregnancy examination, which has played a positive role in the prevention of mother to child transmitted diseases.

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It is estimated that more than 70-1.6 million newborns will suffer from congenital infection every year. According to the statistics of the Ministry of health, there are about 120 million hepatitis B virus carriers in China, and 40% of pregnant women with hepatitis B virus carriers can transmit the virus to the fetus. In addition, domestic investigation found that the infection rates of cytomegalovirus and Toxoplasma gondii in newborns in China are as high as 1% - 2%. It has been confirmed that intrauterine infection is an important cause of congenital defects and disabilities.