What are the causes of high uric acid in chronic nephritis

summary

Some time ago, my uncle found out that uric acid was on the high side. At that time, the doctor asked him to pay attention to it. This high uric acid may cause many diseases, especially in diet. Now he has been very careful. Let's talk about the causes of high uric acid in chronic nephritis.

What are the causes of high uric acid in chronic nephritis

The first reason is that uric acid is the end product of purine metabolism. Under normal circumstances, 2 / 3 of uric acid synthesized by human body is excreted by kidney. Hyperuricemia can be caused by purine metabolism disorder or uric acid excretion disorder. If the long-term blood uric acid is very high, mainly in patients with gout is not well controlled, can also cause uric acid nephropathy.

The second reason is: high uric acid can be seen in renal lesions, but also in other lesions, high uric acid can not be determined to be caused by nephritis, uric acid is the end product of purine metabolism in nucleic acid, in addition to a small part of liver decomposition damage, most of the renal excretion, blood uric acid after glomerular filtration 90% is reabsorbed, so its clearance rate is low.

The third reason is: the increase of uric acid is mainly seen in gout, and it is often accompanied by the increase of serum uric acid when the renal function is decreased. It can be seen in kidney diseases such as acute and chronic nephritis, pyelonephritis, hydronephrosis, etc. Therefore, high uric acid is related to nephritis.

matters needing attention

If the renal function is damaged, uric acid is more likely to stay in the blood and increase its content. It also needs to be combined with medical history and examination to determine the cause of uric acid formation. Patients with high uric acid need to pay attention to drinking more water to promote the excretion of uric acid, so as to avoid other diseases.