How is disulfiram like reaction treated

Update Date: 2023-09-23 Source: Network

summary

In my opinion, disulfiram like symptoms may be different in different periods. After taking cephalosporin and antiviral oral liquid, because the symptoms have not been relieved, we also take it today. In the evening, the leaders invited the customers to dinner. I drank two cups of Baijiu with my client and was sent to the emergency room. The doctor asked the history of the disease, saying that it was because he had taken the cephalosporin and Baijiu liquor to produce a disulfide like reaction.

How is disulfiram like reaction treated

The main manifestations include facial flushing, conjunctival congestion, blurred vision, severe pulsation of blood vessels in the head and neck or pulsatile headache, dizziness, nausea, vomiting, sweating, dry mouth, chest pain, myocardial infarction, acute heart failure, dyspnea, acute liver injury, convulsion and death. Blood pressure may drop during physical examination, Your clinical manifestations are basically the same as above. You should stop taking drugs and alcohol products in time

Second: according to the doctor's advice, 5-10mg dexamethasone was added into glucose solution for intravenous drip or push, fluid infusion and diuresis, and vasoactive drugs were given according to the patient's condition. The patient's consciousness, body temperature, pulse, respiration, heart rate, heart rate, blood pressure, urine volume and other clinical changes were closely observed, and the nursing records of the patient's condition were made

Third: symptomatic treatment. Patients with nausea and vomiting can be given metoclopramide 10mg intramuscular injection; patients with drowsiness and unconsciousness can be given naloxone antitherapy. Patients with shock can be quickly supplemented with crystalloid fluid, and when necessary, dopamine and other pressor drugs can be given to shorten the hypotension period. Patients with angina pectoris need to improve coronary circulation

matters needing attention

In general, continuous oxygen inhalation and ECG monitoring are needed. If blood pressure is reduced, pressor drugs are needed. Patients in coma need to use naloxone and other drugs.