What causes cleft lip?

summary

Every expectant mother hopes that her baby can be born healthily. From the moment she learns that she is pregnant, she begins to fantasize about her baby. For her future baby, she is full of infinite expectations and imagination. What causes cleft lip? Let's talk about it

What causes cleft lip?

Such as vitamin deficiency during pregnancy, especially folic acid deficiency during pregnancy; The mother was infected with virus during pregnancy, such as upper respiratory tract infection, rubella, etc; Exposure to X-ray, computer radiation, etc; Taking antiepileptic drugs, steroids or anti-tumor drugs, antihistamines, long-term exposure to pesticides, long-term tobacco and alcohol stimulation, etc. may cause a series of fetal cleft lip and palate, such as genetic mutations;

Genetic studies have proved that fetal cleft lip and palate is a polygenic genetic disease, and 20% - 30% of the patients have positive genetic factors. Generally, the probability of cleft lip and palate in the first fetus is 1 / 600. If the first fetus is cleft lip and palate, the probability of cleft lip and palate in the second fetus is 3 / 100. If a baby's brother or sister also has this kind of fetal cleft lip and palate, then the baby is 30 to 40 times more likely to have this kind of defect than other babies. We often see similar deformities in the relatives of patients.

Endocrine disorders, due to mental or traumatic factors, such as strong mental stimulation, physical injury, etc; Nutritional factors, severe vomiting, anorexia and partial eclipse in early pregnancy lead to the deficiency of vitamin D, folic acid, iron and calcium, and also lead to fetal cleft lip and palate.

matters needing attention

Expectant mothers must pay close attention to medication during pregnancy, because many drugs have teratogenic effect, so improper medication can lead to fetal malformation and cleft lip and palate. In particular, some antiepileptic drugs have the most obvious teratogenic effect.