Chronic renal failure symptoms?

summary

Chronic renal failure is a chronic progressive renal impairment caused by various causes, resulting in a significant atrophy of the kidneys and failure to maintain basic functions. * clinical syndrome characterized by retention of metabolites, imbalance of water, electrolyte, acid-base, and systemic involvement are the main manifestations of chronic renal failure. What are the symptoms of chronic renal failure?

Chronic renal failure symptoms?

Anemia is a necessary symptom of uremic patients. The degree of anemia is parallel to the degree of uremia (renal function), and the decrease of erythropoietin is the main reason. Bleeding tendency can be manifested as skin and mucous membrane bleeding, which is related to increased platelet destruction, prolonged bleeding time, abnormal white blood cells, decreased white blood cells, weakened chemotaxis, phagocytosis and bactericidal ability, and prone to infection.

Physical discomfort: due to the accumulation of toxins and wastes in the body, the patient may feel uncomfortable. Symptoms include nausea, vomiting, poor night sleep, loss of appetite, itching and fatigue. Edema: some patients will have edema. Decreased urine volume and frequent urination (especially at night). Edema of hands, feet and ankles. Other symptoms include shortness of breath and swelling around the eyes.

Anemia is a necessary symptom of uremic patients. The degree of anemia is parallel to the degree of uremia (renal function), and the decrease of erythropoietin (EPO) is the main reason. Chronic renal failure is a kind of clinical syndrome which is composed of a series of clinical symptoms, biochemical endocrine and other metabolic disorders. The interval from the onset of primary disease to the beginning of renal insufficiency can be several years to more than ten years.

matters needing attention

We should try our best to make clear the cause of chronic renal failure. We should make clear whether the renal damage is mainly glomerular damage, or interstitial tubule disease, or renal vascular disease, so as to provide targeted treatment according to the clinical characteristics. We should find out the reversible factors that promote the progressive deterioration of renal function in chronic renal failure, such as infection, drug-induced renal damage, metabolic acidosis, dehydration, heart failure, rapid and low blood pressure, etc. We should pay attention to find some factors that aggravate the progressive deterioration of renal function in chronic renal failure, such as hypertension, hyperlipidemia, hypercoagulable state, high protein diet intake, large amount of proteinuria and so on.