What is an eosinophilic adenoma?

summary

Eosinophilic adenoma, also known as large eosinophilic granuloma, is a rare benign tumor of salivary gland. The histogenesis of eosinophilic adenoma is not fully understood. It may come from ductal epithelium or ductal myoepithelial cells. What is an eosinophilic adenoma? Let's talk about it

What is an eosinophilic adenoma?

Eosinophilic adenomas mainly occur in parotid gland, accounting for less than 1% of parotid gland tumors. Most of them occur in one side, and some cases can also occur in both sides. Sometimes it can be seen in submandibular gland, palatal gland, buccal gland, etc. It often occurs in elderly women, and the onset age is more than 50 years old.

Eosinophilic adenoma is the clinical manifestation of benign tumor, the tumor volume is generally small, the diameter is generally not more than 5 cm, the growth is slow, the patient does not have any discomfort. The tumor was round or oval, active, soft and without adhesion to the skin.

Microscopically, the tumor cells were large, well-defined, round or polygonal, with granular cytoplasm and eosinophilic staining. The nucleus is round or ovoid with deep staining and even pyknosis. Nucleoli are visible, but mitotic figures are rare. The cells arranged into solid trabeculae or masses, sometimes in glandular lobular arrangement, but did not form glandular lumen. There is fibrous connective tissue stroma between the tumor cell masses, which separates the epithelial masses into leafy components. There is no lymphoid tissue in the stroma, or occasionally a small number of lymphocytes, but generally no lymphoid follicles.

matters needing attention

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