What are the anti rejection drugs and side effects of liver transplantation

summary

When liver disease is more serious or has spread to endanger the safety of patients, liver transplantation should be performed, that is to transplant the diseased liver out of the body and replace it with a healthy and normal liver. Now let's talk about anti rejection drugs and side effects of liver transplantation.

What are the anti rejection drugs and side effects of liver transplantation

First: tacrolimus: with strong immunosuppressive characteristics, its drug intensity is 100 times of cyclosporin A. The rejection rate is low; for patients who can not receive cyclosporine treatment due to side effects (liver function damage) or whose anti rejection effect of cyclosporine is not ideal, doctors generally choose this drug as a substitute. This drug does not cause hirsutism or gingival hyperplasia (and therefore does not affect appearance).

Second, the mechanism of rejection after organ transplantation is very complex, and the effect of anti rejection drugs has some limitations, even the maximum dose of single drug can not completely prevent or inhibit the occurrence of rejection after transplantation. Therefore, patients after transplantation can not only take one anti rejection drug, often choose to use several anti rejection drugs combined.

Thirdly, when the symptoms of liver disease lead to a serious decline in the quality of life of patients, it also becomes one of the main indications of liver transplantation. The common immunosuppressive regimen after liver transplantation, the selection and treatment of immunosuppressive agents after liver transplantation, each unit has its own experience and experience, but the basic principles of drug use are as follows: the principle of minimizing toxic and side effects, the principle of individualization.

matters needing attention

After liver transplantation, the main problem for patients is rejection. So we should take appropriate anti rejection drugs according to the doctor's instructions. Different anti rejection drugs are selected according to the side effects of anti rejection drugs.