How is acquired hyperlipoproteinemia to return a responsibility?

summary

Hyperlipoproteinemia refers to the increase of plasma cholesterol (TC) and / or triglyceride (TG). In fact, it is a manifestation of the elevation of one or several types of lipoprotein in plasma. In recent years, it has been gradually recognized that the decrease of HDL-C (high density lipoprotein cholesterol) in plasma is also a disorder of lipid metabolism. How is acquired hyperlipoproteinemia to return a responsibility? Let's talk about it

How is acquired hyperlipoproteinemia to return a responsibility?

In addition to the high basic value, the main causes of human borderline hypercholesterolemia are dietary factors such as high cholesterol and high saturated fatty acid intake and overweight caused by excessive calories, followed by age effect and female menopause.

Mild hypercholesterolemia refers to plasma TC (cholesterol) concentration of 6.21-7.49 mmol / L (240-289 mg / dl) or LDL of 4.15-5.41 mmol / L (160-209 mg / dl). Most of the patients with mild hypercholesterolemia may be caused by the above-mentioned borderline hypercholesterolemia with genetic abnormalities. Due to the existence of abnormal genes, the rate of LDL catabolism decreased, the synthesis of LDL increased or the structure of LDL changed.

Severe hypercholesterolemia refers to plasma cholesterol concentration more than 7.51mmol/l (290mg / dl) or LDL-C > 5.44mmol/l (210mg / dl). The best example of severe hypercholesterolemia is heterozygous familial hypercholesterolemia (FH). In general population, heterozygote FH incidence rate is 1/500, while severe hypercholesterolemia is 5/100 in adults. Obviously, many severe hypercholesterolemia are caused by other genetic abnormalities.

matters needing attention

The purpose is to reduce plasma cholesterol and maintain balanced nutrition. Besides lowering cholesterol, exercise and weight loss can reduce triglyceride and increase HDL cholesterol. Diet therapy and lifestyle improvement are the basic measures for the treatment of dyslipidemia. No matter whether or not to carry out lipid-lowering therapy, we must insist on diet control and lifestyle improvement.