What are the symptoms of bone marrow transplantation failure?

summary

We may have heard of leukemia, which is caused by the excessive number of white blood cells in the human body, resulting in a series of diseases. Generally speaking, effective treatment should take the method of bone marrow transplantation to improve some functions of hematopoietic stem cells. What are the symptoms of failure of bone marrow transplantation? Let's talk about it

What are the symptoms of bone marrow transplantation failure?

Hepatic venous occlusive disease (HVO) is characterized by liver pain and weight gain in the early stage, followed by hepatomegaly, jaundice and ascites. Hemorrhagic cystitis, large dose of CTX caused by urgency, frequency, pain and hematuria, serious bleeding.

Thrombotic microangiopathy, manifested as hypertension, edema, neurological manifestations, renal dysfunction, thrombocytopenia, red blood cell fragmentation. Acute graft-versus-host disease (aGVHD), with the improvement of hemogram, patients with skin rash, gastrointestinal function and liver function abnormalities.

Also accompanied by fever, infection. Late complications include interstitial pneumonia, dyspnea and hypoxemia. Hypothyroidism and decreased secretion of growth hormone have a great impact on the reproductive system. Male adults can be in the state of azoospermia, while female patients can disappear ovulation and menstruation after TBI, and individual patients can recover.

matters needing attention

Wear clean and soft underwear to avoid scratching the skin. Pay attention to the color, time and area of the rash. Don't scratch the skin when the skin itches. Keep the sheets clean and change underwear frequently. Keep your skin clean. Use 1:2000 chlorhexidine daily in laminar flow clean room, and use warm water for whole body bath in laminar flow clean room.