Symptoms of gossypol poisoning

summary

Poisoning caused by ingestion of gossypol. When raw cottonseed oil is pressed, most of gossypol is moved into the oil, and the content of gossypol in the oil can reach 1% ～ 1.3%. Free gossypol can not only damage male testis and reduce sperm, but also cause amenorrhea and uterine atrophy in women. People who eat crude cottonseed oil in cotton producing areas may have chronic poisoning. Symptoms of gossypol poisoning? Let's talk about it

Symptoms of gossypol poisoning

The former is characterized by burning skin but no sweat, accompanied by dizziness, fatigue, irritability, nausea, pruritus, etc; Hypokalemia was mainly characterized by weakness, numbness, thirst, palpitation and paresis.

Some patients had abnormal ECG. Women and young adults are more likely to have the disease. Hypokalemia can lead to death if not treated in time. The treatment is mainly symptomatic, such as liver protection, potassium, detoxification and so on.

The heart rate was 100 beats / min, the rhythm was regular, the first heart sound was weakened, and no pathological murmur was found in each valve area. Flat abdomen, mild tenderness in upper abdomen, no rebound pain, untouched liver and spleen under ribs, Murphy's sign (--), mobile voiced voice (--), no percussion pain in both kidney regions, physiological curvature of spine, no deformity of limbs.

matters needing attention

The toxicity of crude cottonseed oil was publicized in cotton producing areas. The cottonseed should be crushed, steamed and fried, and then pressed for oil. The free gossypol can be changed into binding gossypol by heating, and the toxicity can be reduced. Crude oil is refined with alkali to remove poison. The free gossypol in cottonseed oil exceeding the standard shall not be sold, but shall be refined by adding alkali.