Rapid deterioration of myasthenia gravis

summary

Myasthenia belongs to the category of eyelid, asthenopia and flaccidity. In the treatment of flaccidity diseases such as myasthenia, this traditional Chinese medicine attaches great importance to heat pathogen, and takes "heat induced body fluid injury, muscle and pulse dystrophy" as the important pathogenesis of this syndrome. For example, myasthenia can be treated by the combination of traditional Chinese and Western medicine, which can effectively remove some diseases. Now let's invite experts to introduce how to do with the rapid deterioration of myasthenia gravis.

Rapid deterioration of myasthenia gravis

Treatment 1: myasthenia gravis is an autoimmune disease, cholinesterase inhibitors, glucocorticoids, immunoglobulin are commonly used in the treatment of drugs, related studies show that the use of glucocorticoid prednisone oral combined with intravenous immunoglobulin treatment of myasthenia gravis better.

Treatment 2: glucocorticoid has a wide range of regulatory effects on the immune system, and has become one of the main treatment methods in traditional treatment. However, long-term large-scale use of hormone has serious adverse reactions, especially in myasthenia gravis crisis, short-term high-dose pulse therapy can inhibit the release of presynaptic membrane acetylcholine, which may lead to the aggravation of myasthenia gravis. When respiratory muscle paralysis occurs, ventilator should be used.

Treatment 3: immunoglobulin can provide a large number of idiotypic antibodies, which can neutralize pathological autoantibodies and prevent them from acting on autoantigens; at the same time, it can reduce the production of autoantibodies; accelerate the degradation and metabolism of IgG antibodies; inhibit pathological cytokines; regulate the function of T cells and neutralize super antibodies, so as to reduce toxic T cells; and; It can compete or inhibit the binding of antibody circulating immune complex with autoantigen and enhance the inactivation of circulating immune complex. Nicotinic acetylcholine receptor (nAChR) is the antigen that causes autoimmune response in myasthenia gravis. Intravenous immunoglobulin therapy not only improves the clinical symptoms of myasthenia gravis, but also significantly reduces the blood titer of patients after treatment.

matters needing attention

Here I would like to give you a warm tip: we should also do moderate exercise, exercise, and enhance our physique, but we should not exercise too much. We should pay special attention to patients with myasthenia gravis. If they exercise too much, they will aggravate their symptoms. Therefore, we should choose some sports that are conducive to the recovery of hyperthyroidism according to our own physical conditions, and patients with serious illness or long-term bedridden Can rise of patients, should pay attention to the occurrence of bedsore.